Connecting Social Entrepreneurs: Promising Practices in Virtual Exchange examines the challenges of implementing a virtual exchange and promising practices that address them. This case study highlights the William Davidson Institute at the University of Michigan’s M²GATE Program, a virtual exchange connecting undergraduate students from five Michigan campuses with peers in Egypt, Libya, Morocco, and Tunisia to find entrepreneurial solutions to social challenges in the Middle East and North Africa (MENA) region. Through online collaboration, teams developed social entrepreneurship projects and accompanying pitches over an eight-week period with the help of instructors, mentors, and successful entrepreneurs from Michigan and the MENA region.